Abemaciclib Understanding the Prescription Medication

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高级医学编辑药学专业

摘要：Abemaciclib, sold under the brand name Verzenio, is a prescription medication used in the treatment of breast cancer. This drug belongs to the class of medications called cyclin-dependent kinase (CDK) inhibitors and is used to slow down or stop the growth

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2023-06-10 21:22:14 发布

Abemaciclib, sold under the brand name Verzenio, is a prescription medication used in the treatment of breast cancer. This drug belongs to the class of medications called cyclin-dependent kinase (CDK) inhibitors and is used to slow down or stop the growth of cancer cells.

Mechanism of Action:

Abemaciclib inhibits the CDK 4/6 enzymes that promote cell cycle progression and cell proliferation. This stops the abnormal growth of cancer cells, thereby limiting the spread of cancer in the body.

Dosage:

Abemaciclib is available in the form of tablets of 50mg, 100mg, and 150mg strength. The dosage prescribed by the doctor might vary depending on the severity of the disease, individual patient needs, and response to treatment. The standard initial dosage is 150mg twice daily, and the dosage is adjusted based on the patient's condition.

Administration:

The tablets are taken orally, with or without food. Swallow the tablets whole with a glass of water. Do not break, cut, or chew the tablets.

Precautions:

Abemaciclib is a potent medication and can cause severe side effects if not taken appropriately. Before taking this drug, inform your doctor about your medical history, previous medication history, allergies, and any other relevant information.

Abemaciclib can be harmful to pregnant women and their unborn babies. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Women of childbearing age are advised to use a reliable contraceptive method during treatment and for at least three weeks after the treatment's completion.

Possible side effects:

Common side effects include:

● Diarrhea

● Fatigue

● Nausea

● Decreased appetite

Serious side effects include:

● Abdominal pain

● Headache

● Seizures

● Blood clots in the lungs or legs

If you experience any of the severe side effects, contact your doctor immediately.

Conclusion:

Abemaciclib is a potent medication used in the treatment of metastatic breast cancer. It helps to slow down or stop the growth of cancer cells. However, the medication must be used under medical supervision, and any adverse effects must be immediately reported to the doctor.